By George M. Rodgers
This finished quantity discusses the protease ADAMTS13, summarizing the present prestige of uncomplicated and medical study. The 9 authoritative chapters start with a historic standpoint by means of exploration of the biochemistry and structure-function relationships of ADAMTS13 in addition to its general functionality in hemostasis (cleavage of von Willebrand factor). rising learn subject matters for ADAMTS13 are lined, together with its strength function in angiogenesis and different points of mobile biology. extra themes contain laboratory assays for ADAMTS13, inherited ADAMTS13 deficiency, and purchased ADAMTS13 deficiency. A bankruptcy on comparable thrombotic microangiopathic (TMA) issues examines the diversities among TMAs linked to ADAMTS13 deficiency and people no longer linked to ADAMTS13 deficiency. a last bankruptcy experiences the initial details on rising features of ADAMTS13, comparable to the prestige of recombinant ADAMTS13 items and their capability utility.
Comprehensive in its exploration of the ADAMTS13 protease in disease, ADAMTS13: Biology and ailment is an important source for scientific hematologists, transfusion medication physicians, and researchers attracted to hemostasis, vascular biology, biochemistry, and metalloproteases.
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ADAMTS13: Biology and Disease by George M. Rodgers